Alterations in Endocrine Function Assignment Paper

Alterations in Endocrine Function – Discussion Part One

This week’s graded topics relate to the following Course Outcomes (COs).

1 Analyze pathophysiologic mechanisms associated with selected disease states. (PO 1) Alterations in Endocrine Function Assignment Paper

2 Differentiate the epidemiology, etiology, developmental considerations, pathogenesis, and clinical and laboratory manifestations of specific disease processes. (PO 1)

3 Examine the way in which homeostatic, adaptive, and compensatory physiological mechanisms can be supported and/or altered through specific therapeutic interventions. (PO 1, 7)

4 Distinguish risk factors associated with selected disease states. (PO 1)

5 Describe outcomes of disruptive or alterations in specific physiologic processes. (PO 1)  Alterations in Endocrine Function Assignment Paper

6 Distinguish risk factors associated with selected disease states. (PO 1)

7 Explore age-specific and developmental alterations in physiologic and disease states. (PO 1, 4)

Case: Alterations in Endocrine Function – Discussion Part One

Alterations in Endocrine Function Assignment Paper

Ms. Blake is an older adult with diabetes and has been too ill to get out of bed for 2 days. She has had a severe cough and has been unable to eat or drink during this time. She has a history of Type I diabetes. On admission her laboratory values show:

Sodium (Na+) 156 mEq/L

Potassium (K+) 4.0 mEq/L  Alterations in Endocrine Function Assignment Paper

Chloride (Cl–) 115 mEq/L

Arterial blood gases (ABGs) pH- 7.30; Pco2-40; Po2-70; HCO3-20

Normal values

Sodium (Na+) 136-146 mEq/L

Potassium (K+) 3.5-5.1 mEq/L Alterations in Endocrine Function Assignment Paper

Chloride (Cl–) 98-106 mEq/L

Arterial blood gases (ABGs) pH- 7.35-7.45

Pco2- 35-45 mmHg

Po2-80-100 mmHg

HCO3–22-28 mEq/L

• List five (5) reasons on why she may have become bed ridden?
• Based on these reasons what tests would you order?
• Describe the molecular mechanism of the development of ketoacidosis. Alterations in Endocrine Function Assignment Paper