The Case Study Of Patient Suffering From Migraine
The Case Study Of Patient Suffering From Migraine
Pathophysiology
The case study of a 24 year-old female with severe right-sided headache, photophobia, nausea and vomiting shows that she is suffering from migraine (Bickley, 2017). This is because those are the characteristic symptoms of the condition (Hammer & McPhee, 2018)The Case Study Of Patient Suffering From Migraine. The purpose of this paper is to look at the pathophysiology of migraine and any racial or ethnic etiological factors that may be involved.
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Neurological and Musculoskeletal Pathophysiologic Processes
Migraine usually occurs due to neurovascular events in the brain. It is a neurobiological condition that is caused by vasodilatation as a result of the release of neurotransmitters from adjacent neurons. The cause is an abnormal activation of the trigeminocervical afferents in the brain. The alteration of brain blood flow by aminergic brainstem nuclei (through an ion channel) and other nuclei causes the severe pain due to nociceptive control (McCance & Huether, 2019)The Case Study Of Patient Suffering From Migraine. The musculoskeletal dysfunction experienced in migraine is caused by interactivity of the cervical and trigeminal systems in the brain (Hammer & McPhee, 2018; McCance & Huether, 2019). It is these neurovascular events that cause pain, sensitivity to light, nausea, and vomiting. The presence of N/V means that the chemoreceptor trigger zone or CTZ in the area postrema of the brain stem is also involved.
Racial/ Ethnic Variables and Interaction of the Processes
There is a strong genetic component to migraine. Specifically, mutations in the gene ATP1A2 have been cited as being responsible by some authors. Thus studies with twins have already proven a strong familial involvement in migraine, with Caucasian non-Hispanic Whites more affected than African Americans and Hispanics (Hammer & McPhee, 2018; McCance & Huether, 2019)The Case Study Of Patient Suffering From Migraine. The genetic predisposition and environmental factors such as stress interact as processes to cause symptoms.
References
Bickley, L.S. (2017). Bates’ guide to physical examination and history taking, 12th ed. Wolters Kluwer.
Hammer, D.G., & McPhee, S.J. (Eds). (2018). Pathophysiology of disease: An introduction to clinical medicine, 8th ed. McGraw-Hill Education.
McCance, K.L. & Huether, S.E. (2019). Pathophysiology: The biologic basis for disease in adults and children, 8th ed. Elsevier, Inc The Case Study Of Patient Suffering From Migraine
Pathophysiology
In your Case Study Analysis related to the scenario provided, explain the following:
- Both the neurological and musculoskeletal pathophysiologic processes that would account for the patient presenting these symptoms.
- Any racial/ethnic variables that may impact physiological functioning.
- How these processes interact to affect the patient.
CASE STUDY SCENARIO
Patient is a 24-year-old female administrative assistant who comes to the emergency department with a chief complaint of severe right-sided headache. She states that this is the sixth time in the last 2 months she has had this headache. She says the headaches last 2–3 days and have impacted her ability to concentrate at work. She complains of nausea and has vomited three times in the last 3 hours. She states, “the light hurts my eyes.” She rates her pain as a 10/10 at this time. Ibuprofen and acetaminophen ease her symptoms somewhat but do not totally relieve them. No other current complaints.
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PS, IF POSSIBLE, PLEASE CITE THE REQUIRED TEXTBOOK LISTED BELOW:
McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier The Case Study Of Patient Suffering From Migraine