Medication Used For The Treatment of Dyslipidemia Assignment
Medication Used For The Treatment of Dyslipidemia Assignment
Select a medication used for the treatment of dyslipidemia or angina. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions, including CAM, of which one should be aware. In addition, share a time when the use of this medication resulted in a positive or negative outcome in a patient for whom you were caring. Include the name of the medication in the subject line so that the medications can be followed. Include references using APA format. Medication Used For The Treatment of Dyslipidemia Assignment
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Lescol (Fluvastatin Sodium) belongs within the HMG-CoA reductase inhibitor medication classification. HMG-CoA acts as the initially dedicated enzyme of the mevalonate path and acts by facilitating the rate-reducing phase of cholesterol synthesis within the liver that leads to dyslipidemia (Mthembu et al., 2022). Statins act by combatively inhibiting HMG-CoA reductase (Zhang et al., 2020). The baseline molecular framework for Fluvastatin mirrors that of HMG-CoA, which enables them to be well fitted within the baseline enzyme’s locales of action.
The generated binding action leads to the development of combative levels with the underlying native substrate, HMG-CoA. As a result, there is an inhibition of the extent of mevalonate generation extents. The production of cholesterol is therefore reduced since mevalonate acts as the subsequent molecule within the baseline cascade for the generation of cholesterol (Zhang et al., 2020). Also, the reduced levels of cholesterol extent within the bloodstream by Fluvastain lead to an elevation of expression levels of LDL receptors within liver hepatocytes. Moreover, there is an increased extent of LDL breakdown activation.
Hints for Monitoring, Side Effects, and Medication Interactions
Lescol may lead to an increased extent of liver enzymes, which necessitates routine monitoring of patients’ liver enzymes. Also, there is the necessity for the patient to be continually educated to stop taking or even eating grapefruit. The context is that grapefruit increases the chances of inhibition of the baseline liver enzymes, and elevates the levels of Lescol within the patient’s bloodstream as the drug is not readily secreted through urine or feces (Ramsamooj & Preuss, 2022)Medication Used For The Treatment of Dyslipidemia Assignment. Also, if the patient complains of muscle pain then there is the need for assessing CPK extent to guarantee a lack of diagnosed rhabdomyolysis.
Possible side effects of Fluvastatin use include problems in breathing, bowel problems, increased feeling of tiredness, shortness of breath, reduced appetite, swollen face, and yellowing of one’s skin. A complementary and Alternative Medicine (CAM) that requires care when used together with Lescol is rhabdomyolysis due to the aptitude of generating fatal healthcare outcomes (Ramsamooj & Preuss, 2022)Medication Used For The Treatment of Dyslipidemia Assignment. The context is increased when a patient is suffering from hypertension, which greatly increases the chances of the realization of statin-induced rhabdomyolysis.
References
Mthembu, S. X. H., Orlando, P., & Silvestri, S. (2022). Impact of dyslipidemia in the development of cardiovascular complications: Delineating the potential therapeutic role of coenzyme Q10. Biochimie. https://doi.org/https://doi.org/10.1016/j.biochi.2022.08.018
Ramsamooj , H., & Preuss, C. V. (2022). Fluvastatin. StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK430685/.
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Zhang , X., Xing , L., & Jia, X. (2020). Comparative Lipid-Lowering/Increasing Efficacy of 7 Statins in Patients with Dyslipidemia, Cardiovascular Diseases, or Diabetes Mellitus: Systematic Review and Network Meta-Analyses of 50 Randomized Controlled Trials. Cardiovascular Therapeutics , 2020(3987065). https://doi.org/10.1155/2020/398706 Medication Used For The Treatment of Dyslipidemia Assignment